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Parkinson’s and Movement Disorders

For information on Parkinson’s and Movement Disorders clinical trials, please contact Salma Khalil
 

Current Recruiting Studies

Canadian Advanced Parkinson DUODOPA-Treated Patients Observational Study Evaluating Long-Term Health Outcome in Centers of Excellence (CADENCE)

From clinicaltrials.gov:

This is an open-label, postmarketing, observational study to document health outcomes, in Canadian patients with advanced Parkinson’s disease and long-term treatment with Duodopa (levodopa/carbidopa intestinal gel).

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A Randomized, Double-Blind, Placebo-Controlled Multiple Dose Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of ABBV-8E12 in Progressive Supranuclear Palsy

From clinicaltrials.gov:

The purpose of this study is to assess efficacy, safety, tolerability, and pharmacokinetics of ABBV-8E12 in subjects with progressive supranuclear palsy (PSP).

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Multicenter, randomized, double-blind, placebo controlled study to assess the efficacy, safety, pharmacokinetics, and pharmacodynamics of GZ/SAR402671 in patients with early-stage Parkinson’s disease carrying a GBA mutation or other pre-specified variant.

From clinicaltrials.gov:

Primary Objectives:

Part 1: To determine the safety and tolerability of GZ/SAR402671 administered orally, as compared to placebo in patients with early-stage Parkinson’s disease (PD) carrying a GBA mutation or other pre-specified variants.
Part 2: To determine the efficacy of GZ/SAR402671 administered orally daily, as compared to placebo in patients with early-stage Parkinson’s disease carrying a GBA mutation or other pre-specified variants.

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