News
A young father shares his experience of living with ALS
If we were to ask you to pick an object defining compassion, what would you choose? For Phillipe B, it is his electric toothbrush. Recently diagnosed with amyotrophic lateral sclerosis (ALS), Phillipe shares his experience of the disease, and his vision of a life with...
Interview with Norman MacIsaac: I’m not a victim of ALS
I’m not a victim of ALS, I’m part of an army of people working to end ALS. We can use many words to try and define Norman MacIsaac: husband, father, friend, author, unapologetic optimist, ALS ambassador, patient advocate, leader. Today we are sharing a part of his...
Dr. Ducharme talks about the Jokers laugh
The Joker's laughter exists for real (Translated from lapress.ca) "The laughter of the Joker, excessive and stretching inordinately over time, is not an invention of the creators of the Machiavellian character. It bears a name: the pseudobulbar affect (PBA) And some...
Parkinson Canada Superwalk
Parkinson Canada SuperwalkFor more than 30 years participants from across the country have come together to show one another that they are not alone. Now, guided by the relentless perseverance of people living with Parkinson's standing up to their diagnosis more than...
Burgers to Beat MS
Burgers to Beat MSThe CRU and the MS clinic help raise money towards MS Research and Support programs. Thank you to Sean Carlin for organizing our participation! On August 22nd, $2 from every Teen Burger sold from A&W will go toward those living with MS.
Highest global enroller for brain tumour clinical trial
Highest global enroller for brain tumour clinical trialDr. Petrecca and his team (Josephine Chu and Adrien Poulin) have received a 2018 Scimega Network Champion Award for their outstanding performance as the highest global enroller for their U.S. Biotech Sponsor’s...
CTV with Dr. Paul Giacomini on MS in Canada
Your Morning with Dr. Paul Giacomini Canada has one of the highest rates of MS in the world. Join Dr Giacomini on CTV's "Your Morning" as he talks about why MS rates are so high in Canada and what is being done to fight it.
Dr. Angela Genge, recipient of the Forbes Norris Award
Dr. Genge awarded the 2018 Forbes Norris Award A big congratulations to our inspiring director, Dr. Angela Genge, on receiving the Forbes Norris award at the ALS MND symposium in Glasgow, Scotland! She is recognized for her exceptional care and compassion towards ALS...
The first on the INTRAGO brain tumour trial in Canada
The first on the INTRAGO brain tumour trial in Canada Le premier de l'essai INTRAGO sur les tumeurs cérébrales au Canada Glioblastoma Multiforme is grade IV brain cancer that is very aggressive. There are currently no cure but research is advancing to find new ways to...
Recent Facebook Posts
Sanofi has released the preliminary results for their ongoing Phase 3 Clinical trial involving patients with Late Onset Pompe Disease (LOPD), in which the CRU is a participating site! They found that their new Enzyme Replacement Therapy showed clinically meaningful improvements in respiratory impairment and mobility. Read more here: www.sanofi.com/en/media-room/press-releases/2020/2020-06-16-14-00-00
La compagnie Sanofi a publié les résultats préliminaires pour un essai clinique en cours de phase 3, impliquant des patients atteints de la maladie Pompe. Le CRU est un site participant! Ils ont constaté que leur nouvelle thérapie de remplacement enzymatique a montré des améliorations cliniquement significatives dans les symptômes respiratoires et dans la mobilité. Plus de détails ici: www.sanofi.com/en/media-room/press-releases/2020/2020-06-16-14-00-00
#TrialTuesday
Aducanumab is a medication that targets beta-amyloid, a protein associated with Alzheimer's disease (AD). The drug has most recently gone through Phase III clinical trials to test its efficacy, which the CRU participated in. The trial was initially terminated due to the unlikelihood of meeting its primary endpoint, but "new analysis of larger dataset showed that aducanumab reduced clinical decline in patients with early AD". Biogen is now applying for FDA approval and will offer the drug to patients previously in clinical trials. This would be one of the first disease modifying therapies for AD.
Aducanumab est un médicament qui cible la protéine bêta-amyloïde qui est associée à la maladie d'Alzheimer. L’URC a récemment participé à l’évaluation de ce médicament durant les essais cliniques de Phase III. L’étude avait initialement été annulée suite à des analyses préliminaires qui démontraient une faible probabilité que le médicament soit efficace. Toutefois, l’analyse d’un échantillon plus grand a trouvé que le médicament aducanumab réduisait la progression chez les patients au stade léger de la maladie d’Alzheimer. La compagnie Biogen fait maintenant demande d’approbation à la FDA et rendra le médicament disponible aux patients qui ont été dans les essais cliniques. Aducanumab serait un des premiers médicaments à modifier le parcous de la maladie d’Alzheimer.
Details:
investors.biogen.com/news-releases/news-release-details/biogen-plans-regulatory-filing-aducanumab...
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Meet Maura! Rencontrez Maura!
"I am a physiotherapist with the ALS clinic. For ALS patients, physiotherapy can be used to maintain and maximize physical strength, function, motion, and well-being. Often aids are suggested to allow patients to remain independent and safe in their mobility. I recommend exercises to maintain flexibility, while preventing and reducing pain. I use different aspects from my training including a modified yoga approach to assist patients with finding ease in their body. "
"Je suis une physiothérapeute à la clinique de la SLA. Pour les patients avec la SLA. La physiothérapie peut être utilisée pour maintenir et maximiser la force physique, la fonction, les mouvements et le bien-être. Souvent, des outils sont suggérés pour permettre aux patients de rester indépendant et en sécurité dans leur mobilité. Je recommende des exercices pour maintenir la flexibilité, tout en prévenant et réduisant les douleurs. J'utilise différents aspects de ma formation, comme une approche modifiée du yoga pour aider les patients à trouver du comfort dans leur corps."
#neuro #neuroscience #neurologicaldisorder #research #montrealneuro #clinicalresearchunit #mcgill #mni #clinicaltrials #cru #theneuro #brainsneed #ALS #SLA #neurodegenerativedisease #strongerthanALS
Meet Kalyna! Rencontrez Kalyna!
"Having difficulties speaking can be one of the hardest parts of the disease. The speech-language pathologist’s role is to help maintain people’s ability to communicate with their loved ones and the wider community by offering strategies and alternatives when speech becomes difficult to understand."
"Avoir des difficultés pour parler peut être l'une des partie les plus douloureuse d'une maladie. Le rôle de l'orthophoniste est d'aider à maintenir la capacité à communiquer avec leurs proches et leur entourage, en offrant des strategies et des alternatives quand le langage devient difficile à comprendre."
#neuro #neuroscience #neurologicaldisorder #research #clinicalresearch #drugdevelopment #openscience #brainscience #montrealneuro #clinicalresearchunit #mcgill #mni #clinicaltrials #cru #theneuro #montrealneuro #brainsneed #ALS #SLA #neurodegenerativedisease #strongerthanALS #scleroselateraleamyotrophique #amyotrophiclateralsclerosis #beatals #endals
Meet Nancy! Rencontrez Nancy!
"My role as a genetic counselor is to help people living with ALS and their family members understand the role genetics has on the disease. Through information giving at the time of a person’s clinical diagnosis and discussion of choosing to do a genetic test, to providing results, in offering the same support to their family members, I am passionate about helping people better understand, interpret and cope with this complex influence. "
"Mon role en tant que conseillère génétique est d'aider les gens avec la SLA et leurs familles à comprendre le rôle que la génétique a sur leur maladie. Je suis celle qui donne ces informations au moment du diagnostic, avec qui l'on discute autour du choix de faire un test génétique ou non, qui accompagne lors des résultats génétiques, et ce à la fois pour les patients et pour leur famille. Je suis passionnée par ce que je fais, particulièrement les aider à mieux comprendre, interpréter et faire face aux résultats génétiques."
#neuro #neuroscience #neurologicaldisorder #research #clinicalresearch #drugdevelopment #openscience #brainscience #montrealneuro #clinicalresearchunit #mcgill #mni #clinicaltrials #cru #theneuro #montrealneuro #brainsneed #ALS #SLA #beatals #endals